Interleukin 2 (IL-2) (also designated T Cell Growth Factor (TCGF) or Aldesleukin or Lymphokine 2) is a T cell stimulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, LAK cells, natural killer cells, monocytes, macrophages and oligodendrocytes. It also induces CTLA-4 and promotes peripheral development of regulatory T cells (Tregs). IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. Contrarily, it is involved in the activation-induced cell death (AICD) that is observed post T cell expansion by increasing levels of Fas on CD4+ T cells.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: IL2/3949
Source: Mouse
Tissue Type/Cancer Type: Colon Tissue

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