Immunoglobulin D (IgD) is one of the Immunoglobins with monomeric structure consisting of δ heavy chains and either κ or λ light chains. It is the major antigen receptor isotype co-expressed with IgM and plays a biological role as a transmembrane receptor molecule on the surface of mature/naive B cells. IgD is detected in the surface/cytoplasm of neoplastic cells of common small B lymphoid cell such as mantle cell lymphoma, small lymphocytic lymphoma, follicular lymphoma and marginal zone lymphoma. It is useful in distinguishing B-cell lineage derived from Lymphomas, Leukemias, and Plasmacytomas.
Intended Use: IVD
Antibody Type: Cytoplasm
Clone: IgD26
Source: Mouse
Tissue Type/Cancer Type: Tonsil and Lymphoid tissues

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