Hypoxia-inducible factor 1-alpha is known as HIF-1-alpha a protein that in humans is encoded by the HIF1A gene. HIF-1 shows to activate hypoxia-responsive genes that are involved in multiple aspects of tumorigenesis and cancer progression which also includes proliferation, metabolism, angiogenesis, invasion, metastasis and therapy resistance. It also plays an important role in cellular and systemic responses to hypoxia. Hypoxia has been clinically demonstrated to predict an adverse treatment outcome in radio therapeutic management of cancer of the head and neck, uterine cervix and soft tissue sarcomas. HIF-1 alpha antibody may be used in analyzing the cancer cell response to therapy.
6 mL (RTU), 10 mL (RTU), 1 mL(Conc.), 0.5 mL (Conc.), 200 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual