FLI-1 is a member of ETS family of transcription factors, also known as Friend leukaemia integration-1. It is involved in cell proliferation, tumorigenesis and blood vessel development. A chromosomal aberration involving FLI-1 is found in patients with Ewing sarcoma. Positive nuclear FLI-1 staining helps diagnosis of Ewing sarcoma and vascular tumors Cytoplasmic staining is also present in benign and malignant breast epithelium and eccrine sweat glands of the skin.
0.5 mL (Conc.), 1 mL(Conc.), 6 mL (RTU), 10 mL (RTU), 50 tests – Xmatrx Elite, 200 tests – Xmatrx Elite