LN3 expressed mainly by antigen presenting cells, B cells of the germinal centers and mantle zones, and additionally by monocytes, macrophages and interdigitating histiocytes, is reactive with a non-polymorphic antigen of the HLA-DR (Ia) region. HLA-DR antigens also occur on a variety of epithelial cells and their neoplastic descendants. LN3 will produce medium intensity staining on B lymphocytes of germinal centers and mantle zones, and high intensity staining of interdigitating histiocytes in T cell zones. HLA-DR is a transmembrane glycoprotein composed of an alpha chain (36 kDa) and a beta chain (27 kDa).
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | LN3 |
| Source | Mouse |
| Tissue Type/Cancer Type | Tonsil |
| Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
