HLA-DR/DP/DQ/DX antibody (also designated HLA class II HLADR / HLADP / HLADQ / HLADX antibody is a major histocompatibility complex (MHC) class II heterodimer cell surface receptor antibody. The major histocompatibility complex (MHC) is a large genomic region that has an important in the immune response to infections. The MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. These are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes.
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | CR3/43 |
Source | Mouse |
Tissue Type/Cancer Type | Lymph Node tissue |
Pack | 6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 160 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides – Xmatrx, 5 slides – Manual |