HLA Class-1 ABC (MHC1) antigens are intrinsic polymorphic membrane glycoproteins encoded by genes located on the short arm of chromosome 6. HLA-A, HLA-B and HLA-C molecules are heterodimers composed of heavy (alpha) chain (44 kDa) and β2-microglobulin light (beta) chain (12 kDa). They play a crucial role in immune system by presenting foreign antigens to cytotoxic T cells for immune recognition. These glycoproteins are expressed on all nucleated cells.
|Tissue Type/Cancer Type||
Tonsil, Lymph node tissues
1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 6 mL – Manual – RTU, 10 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx