HHV-8, also designated as Lana1 or ORF73, is the eighth human herpes virus which is likely to be the etiological agent of Kaposi sarcoma (KS). It is a multifunctional protein that plays a role in the replication and long-term persistence of the viral episomal genome in dividing cells. HHV-8 labels the latent nuclear antigen protein (LNA), which is the product of the viral gene ORF 73. HHV-8 has been found to be associated with three different diseases observed in AIDS patients, multicentric Castleman’s disease, kaposi’s sarcoma and primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities).
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | HHV8/3606 |
| Source | Mouse |
| Tissue Type/Cancer Type | Kaposi’s Sarcoma |
| Pack | 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
