HHV-8, also designated as Lana1 or ORF73, is the eighth human herpes virus which is likely to be the etiological agent of Kaposi sarcoma (KS). It is a multifunctional protein that plays a role in the replication and long-term persistence of the viral episomal genome in dividing cells. HHV-8 labels the latent nuclear antigen protein (LNA), which is the product of the viral gene ORF 73. HHV-8 has been found to be associated with three different diseases observed in AIDS patients, multicentric Castleman's disease, kaposi's sarcoma and primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities).
Intended Use: IVD
Antibody Type: Monoclonal
Clone: HHV8/3606
Source: Mouse
Tissue Type/Cancer Type: Kaposi’s Sarcoma

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