HBcAg is the designation given to the antigenic activity of the 28 nm nucleocapsid core of Hepatitis B Virus. Immunocytochemical staining for HBcAg can provide conclusive evidence for a viral etiology in hepatitis. Furthermore, viral antigenic expression in liver cells can be correlated with the histopathologic changes, thus facilitating investigation into the mechanism of virus-induced injury. HBcAg is not detected in the serum of either acutely or chronically infected individuals. As the patient becomes symptomatic, HBc antibody becomes detectable. This antibody stains Hepatitis B Virus Core Antigen in nuclei of infected cells in tissue sections stained by immunohistochemical techniques.
Intended Use | RUO |
---|---|
Antibody Type | Polyclonal |
Clone | Polyclonal |
Source | Rabbit |
Tissue Type/Cancer Type | Hepatitis |
Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |