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Anti-GM-CSF
SKU: AMC56GP Categories: , ,
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GM-CSF (Granulocyte-Macrophage colony-stimulating factor) also known as colony stimulating factor 2 (CSF2), is a 14.6kDa monomeric hematopoietic growth factor secreted by macrophages, activated T-cells, B-cells, mast cells, NK cells, endothelial cells and fibroblasts. It is a pleiotropic cytokine that stimulates the growth and differentiation of granulocytes, macrophages, erythrocytes, early megakaryocytes and eosinophil from bone marrow progenitor cells. GM-CSF activates effector functions of myeloid cells, thereby linking adaptive and innate immunity and in turn may boost immune-independent tumor progression. GM-CSF also plays a vital role in immune regulation and hematopoiesis.

Intended Use

IVD

Antibody Type

Monoclonal

Clone

CSF2/3403

Source

Mouse

Tissue Type/Cancer Type

Tonsil Tissue

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual