GM-CSF (Granulocyte-Macrophage colony-stimulating factor) also known as colony stimulating factor 2 (CSF2), is a 14.6kDa monomeric hematopoietic growth factor secreted by macrophages, activated T-cells, B-cells, mast cells, NK cells, endothelial cells and fibroblasts. It is a pleiotropic cytokine that stimulates the growth and differentiation of granulocytes, macrophages, erythrocytes, early megakaryocytes and eosinophil from bone marrow progenitor cells. GM-CSF activates effector functions of myeloid cells, thereby linking adaptive and innate immunity and in turn may boost immune-independent tumor progression. GM-CSF also plays a vital role in immune regulation and hematopoiesis.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | CSF2/3403 |
| Source | Mouse |
| Tissue Type/Cancer Type | Tonsil Tissue |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
