The major source of Gastrin in the body is the antropyloric mucosa of the stomach. Significant increases in the antropyloric G-cell (gastrin producers) population occur in a wide variety of clinical conditions such as atrophic gastritis, pernicious anemia, gastric carcinoma, gastric outlet obstruction, Zollinger-Ellison syndrome, duodenal ulcer disease. Neoplastic proliferations of the gastrin producing cells are frequently associated with the Zollinger-Ellison syndrome. Tumor cells in gastrinomas consistently demonstrate immunohistochemical reactivity with gastrin antibodies
Intended Use | IVD |
---|---|
Antibody Type | Polyclonal |
Clone | Polyclonal |
Source | Rabbit |
Tissue Type/Cancer Type | Stomach |
Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |