Anti-Epithelial Membrane Antigen (EMA)


The mucin antigen recognized by Mc-5 is a glycosylated molecule with a molecular mass of 400 kD. The sequence to which this antibody binds is Thr-Arg-Pro-Ala-Pro. Although EMA is primarily located in mammary gland epithelium, other normal epithelia (e.g., lung) will also react against EMA antibody. Staining, however, is the strongest in mammary epithelia. The combination of positive staining for keratin with negative EMA can be used to phenotype the above-mentioned epithelial tumors.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: Mc5
Source: Mouse
Tissue Type/Cancer Type: Breast Ca

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