E-cadherin (123-kD) is a cell surface glycoprotein responsible for Ca 2+ -dependent intercellular adhesion between epithelial cells; it is also called uvomorulin, L-CAM, cell-CAM 120/80 or Arc-1. Alterations in the cell-cell adhesion mechanism mediated by E-cadherin which is lightly associated with alpha catenin may have implications in the metastatic potential of prostate cancer. E-cadherin may also play a role in adhesion of dendritic epidermal T cells to keratinocytes. Clone 36 may be used to investigate the process of tumor invasion
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | 36 |
| Source | Mouse |
| Tissue Type/Cancer Type | Colon Ca |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
