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Anti-E-Cadherin

SKU: AN725GP Categories: , , ,
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Product Description

E-Cadherin is a glycoprotein transmembrane with an important role in epithelial cell adhesion. E-Cadherin may act as a suppressor of invasion in neoplastic progression. The expression of E-Cadherin is reported to be absent or reduced in prostate cancers for example, in comparision with its expression in normal prostate which is uniformly strong. A decreased expression of E-Cadherin is associated with metastatic potential and poor prognosis in breast cancer and esophagus cancer. In combination with p120 Catenin or Cytokeratin it is useful for the differentiation between ductal (E-Cadherin positive) and lobular (E-Cadherin negative) breast carcinomas. It may also help in diagnosis of mesothelioma

Intended Use

IVD

Antibody Type

Monoclonal

Clone

EP6

Source

Rabbit

Tissue Type/Cancer Type

Breast Ca

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual