DatasheetSDS

This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. This MAb recognizes the double stranded DNA in human cells and may be useful in identification of these organelles in cells, tissues, and biochemical preparations. It stains the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells. DNA holds the genetic instructions for the development and function of living things. In living organisms, DNA does not usually exist as a single molecule, but instead as a tightly associated pair of molecules in the shape of a right-handed double helix. During replication and transcription, portions of the helix unwind and become single stranded. Protective proteins surround these single-stranded DNA. Double stranded (ds) DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.