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Anti-Cytokeratin, Low MW

SKU: AM075GP Categories: , , ,
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Product Description

The cytokeratins are a family of water-insoluble proteins (40-70 kD) found in almost all epithelial cell types. The presence of keratin appears to be a highly specific characteristic of various true epithelial cells in-situ and is maintained in epithelium-derived cells in culture, including highly malignant cell lines. Low molecular weight cytokeratin antibody AE1 has proven to be a widespread histological marker for the restricted staining of the epidermal basal layer of skin and almost all epithelially derived tumors. It can be used as a marker for cells of epithelial origin. Combined with other monoclonal keratin antibodies, it may be useful in studying the histogenesis of undifferentiated tumors

Intended Use

IVD

Antibody Type

Monoclonal

Clone

AE1

Source

Mouse

Tissue Type/Cancer Type

Breast Ca

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual