The cytokeratins are a family of water-insoluble proteins (40-70 kD) found in almost all epithelial cell types. Monoclonal cytokeratin antibody AE3 recognizes all basic (Type II) keratins. Since each epithelium contains at least one acidic and one basic keratin, AE3 may be used as a broadly reactive antibody which stains positive for most epithelia and their neoplasms. AE3 has shown great sensitivity and broad specificity for keratins under various conditions of fixation and staining.
|Tissue Type/Cancer Type|
Squamous Cell Ca
0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual