Cytokeratin 8 (52 kD) and 18 (45 kD) comprise a cytokeratin pair as markers for simple epithelia. In most situations, cytokeratin 8 exists in tissues together with cytokeratin 18, but there are exceptions among some normal and abnormal epithelial cells. Therefore, it is useful to use both monoclonal antibodies (8 and 18) in combination with other monoclonal cytokeratin antibodies when studying cytokeratin expression patterns. Clone C-51 is designed for the specific localization of Cytokeratin 8 and does not cross-react with human cytokeratin 7, 17, 18, or 19.
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | C51 |
Source | Mouse |
Tissue Type/Cancer Type | Breast Ca |
Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |