Carcinomas may be classified precisely by the analysis of their keratin patterns. Clone 5D3 recognizes an epitope restricted to a few members of the cytokeratin subclasses, specifically cytokeratins 8 and 18. This antibody reacts with all simple epithelia including glandular epithelium and ciliated pseudostratified columnar epithelium localized in thyroid, female breast, gastrointestinal and respiratory tract. 5D3 may be a useful marker for demonstrating columnar cell differentiation when studying biphasic differentiation of basal cells of respiratory or intermediate epithelium. It may also be possible to use 5D3 in a panel of antibodies for the histological subclassification of some carcinomas such as lung carcinoma or adenocarcinoma
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | 5D3 |
| Source | Mouse |
| Tissue Type/Cancer Type | Colon Ca |
| Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
