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Anti-Cytokeratin 8 &18

SKU: AM131GP Categories: , , ,
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Product Description

Carcinomas may be classified precisely by the analysis of their keratin patterns. Clone 5D3 recognizes an epitope restricted to a few members of the cytokeratin subclasses, specifically cytokeratins 8 and 18. This antibody reacts with all simple epithelia including glandular epithelium and ciliated pseudostratified columnar epithelium localized in thyroid, female breast, gastrointestinal and respiratory tract. 5D3 may be a useful marker for demonstrating columnar cell differentiation when studying biphasic differentiation of basal cells of respiratory or intermediate epithelium. It may also be possible to use 5D3 in a panel of antibodies for the histological subclassification of some carcinomas such as lung carcinoma or adenocarcinoma

Intended Use

IVD

Antibody Type

Monoclonal

Clone

5D3

Source

Mouse

Tissue Type/Cancer Type

Colon Ca

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual