Anti-Cytokeratin 7

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This antibody recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, belongs to type II cytokeratin. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels, which is found in most glandular and transitional epithelia, but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
SKU: AM944GP
Intended Use: IVD
Antibody Type: Monoclonal
Clone: KRT7/760
Source: Mouse
Tissue Type/Cancer Type: PancreasEndometrium