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Anti-Cytokeratin 14

SKU: AM146GP Categories: , ,
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Product Description

Keratins are intermediate filament proteins expressed by epithelial cells in cytoplasm. Mitotically active basal layers of most stratified squamous epithelia cells express 10% to 30% of their total protein as keratin. Cytokeratin 14 (CK14) is a 50-kDa keratin expressed in abundance in epidermal cells, basal cells, mesothelial cells, stratified epithelial cells, and myoepithelial cells in various tissues including prostate and breast. CK14 is helpful in the identification of breast cancer with basal phenotype. Monoclonal antibody to cytokeratin 14 may be helpful in distinguishing cells types of human mammary gland, thus it may also be used to study histogenesis of breast carcinoma

Intended Use

IVD

Antibody Type

Monoclonal

Clone

LL002

Source

Mouse

Tissue Type/Cancer Type

Squamous Cell Ca

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual