CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is composed of a single Ig V like extracellular domain, a transmembrane domain and an intracellular domain and belongs to immunoglobulin (Ig) gene superfamily. It is structurally homologous to CD28 and is expressed on CD4+ cytotoxic T cells. CTLA-4 is a strong inhibitor of T-cell activation and is functions in T-cell apoptosis. CTLA-4 is also found intracellularly in regulatory T-cells and is important for their function.
6 mL (RTU), 10 mL (RTU), 1 mL(Conc.), 0.5 mL (Conc.), 50 tests – Xmatrx Elite, 160 tests – Xmatrx Elite, 5 slides – Manual, 5 slides – Xmatrx