Carboxypeptidase A1/ CPA1 is a 419 amino acid zinc metalloenzymes belongs to the peptidase M14 family. It is a secreted monomeric protein involved in zymogen inhibition and functioning to block enzyme activation pathways. It is highly expressed in pancreatic tissue and functions as a pancreatic exopeptidase. CPA1 plays a key role in protein digestion and degradation by using zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins. Abnormal levels of CPA1are observed in pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | CPA1/2712 |
| Source | Mouse |
| Tissue Type/Cancer Type | Pancreas Tissue |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
