Carboxypeptidase A1/ CPA1 is a 419 amino acid zinc metalloenzymes belongs to the peptidase M14 family. It is a secreted monomeric protein involved in zymogen inhibition and functioning to block enzyme activation pathways. It is highly expressed in pancreatic tissue and functions as a pancreatic exopeptidase. CPA1 plays a key role in protein digestion and degradation by using zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins. Abnormal levels of CPA1are observed in pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: CPA1/2712
Source: Mouse
Tissue Type/Cancer Type: Pancreas Tissue

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