Anti-COX2, Clone COX2/3320R


The enzyme cyclooxygenase (COX), also known as prostaglandin H synthase or prostaglandin endoperoxide synthase, consists of two isoforms, COX-1 and COX-2. Both isoforms are associated with inner membranous compartments and represent key enzymes in the conversion of arachidonic acid to prostaglandin. COX-1 is constitutively expressed in most cell types and is involved in the homeostasis of various physiological functions, while COX-2 is considered to be a mitogen-inducible form, associated with biologic events such as injury, inflammation, and proliferation. COX-2 plays an important role in carcinogenesis of various human cancers, including colorectal cancer and cervical cancer. COX-2 has been studied as a key rate-limiting enzyme for prostanoid biosynthesis.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: COX2/3320R
Source: Rabbit
Tissue Type/Cancer Type: Colon

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