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Anti-Collagen IV

SKU: AM379GP Categories: , , ,
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Product Description

This antibody reacts with collagen IV and does not cross-react with other collagen types. It does not cross-react with human vitronectin, fibronectin or chondroitin sulfate A, B, or C. Collagen IV is present in the basal lamina and does not form fibrils or fibers. The positive or negative demonstration of basal lamina using immunostaining helps to distinguish some types of benign lesions from malignant tumors such as tubular carcinoma of the breast. Schwannomas and leiomyomas and their well differentiated malignant counterparts usually immunoreact in a characteristic fashion to the monoclonal antibody for type IV Collagen. The vascular nature of neoplasms such as hemangiopericytoma and epithelioid hemangio-endothelioma can be revealed by type IV Collagen with more reliability than other non-specific stains

Intended Use

IVD

Antibody Type

Monoclonal

Clone

COL-94

Source

Mouse

Tissue Type/Cancer Type

Skin

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual