Menu

Anti-Claudin-5

SKU: AN718GP Categories: , , ,
Clear

Product Description

Claudin superfamily proteins are key functional and structural components of tight junctions. The Claudin superfamily consists of many structurally related proteins involved in paracellular transport in humans. Claudins are located in all tight junction that includes both epithelial and endothelial cells in tight junction bearing tissues. Claudin-5 is a member of the Claudin superfamily. Claudin-5 ?mutations are seen in patients with velocardiofacial syndrome. Claudin-5 been used as a marker for endothelial lesions. Claudin-5 expression in tumors, has been found associated with lung adenocarcinoma and squamous carcinoma(2). In serous ovarian adenocarcinoma increased Claudin-5 expression is associated with aggressive behaviour.

Intended Use

IVD

Antibody Type

Monoclonal

Clone

EP224

Source

Rabbit

Tissue Type/Cancer Type

Lung Squamous Ca

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual