Datasheet SDS

Chromogranin A is a 49-kDa acidic glycoprotein that belongs to the granin family, a principal component of dense-core granules in neuroendocrine cells, with which its expression generally correlates. Chromoganin A and hormones are co-secreted from neuroendocrine cells during the secretory granule exocytotic process. Chromoganin A itself can also be degraded into a series of smaller biologically active peptides, such as pancreastatin, catestatin, and vasostatins I and II. This antibody reacts with chromogranin A in neuroendocrine cells of the human stomach, colon, pancreas, adrenal gland, peripheral nerve tissue and carcinoid tumors.