CDX-2 antibody is a homeobox gene that encodes an intestine-specific transcription factor. The CDX-2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal type gastric cancer and intestinal metaplasia of the stomach. In human colorectal cancer, the expression of both CDX-2 and carbonic anhydrase 1, a gene regulated by CDX-2, is reduced or absent. CDX-2 is one of the key regulators in defining pathways for coordinate control of drug metabolism in the gastrointestinal tract
Intended Use: IVD
Antibody Type: Monoclonal
Clone: EP25
Source: Rabbit
Tissue Type/Cancer Type: Colon Ca