The CD95 (Fas) protein is a cell surface receptor belonging to the tumor necrosis factor (TNF) family that transduces death signaling on engagement by multimeric Fas ligand (CD95L), of which there are eight in its membrane –bound form or in its soluble form resulting from cleavage by a putative metalloproteinase. CD95 is a widely expressed protein. During embryonic and postembryonic development, many cells die by means of apoptosis. This plays a major role in determining morphological and functional maturity in a variety of systems, including the formation of the neural network and clonal deletion of autoreactive T cells.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: EP208
Source: Rabbit
Tissue Type/Cancer Type: Tonsil