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Anti-CD82

SKU: AN757GP Categories: , , ,
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Product Description

CD82, also known as metastasis suppressor Kangai-1 (KAI1), is a member of the tetraspanin protein family and is a metastasis suppressor implicated in biological processes ranging from fusion, adhesion and migration to apoptosis and cell-morphology alterations. In tumors, the expression of CD82 has been shown to be downregulated in tumor progression. CD82 can be activated by p53 through a consensus binding sequence in the promoter. Loss of p53 function, which is commonly observed in many types of cancers, may lead to the downregulation of the CD82 gene. The correlation between lower or no expression of CD82 and poor tumor prognosis is observed in many types of tumors, including prostate, breast, colon, stomach, bladder, lung, liver, pancreas, and ovary tumors

Intended Use

IVD

Antibody Type

Monoclonal

Clone

EP160

Source

Rabbit

Tissue Type/Cancer Type

Adeno Ca

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual