DatasheetSDS

The CD8 antigen, also known as T8 or Leu2 or Lyt2 or T cell coreceptor, is a dimer with a molecular mass of 32 kD. The T8 antigen is expressed by the suppressor/cytotoxic subset of T lymphocytes which comprise most of the cortical thymocytes and approximately 30% of peripheral blood T cells. Studies have demonstrated that increased levels of T8+ cells are associated with viral infections such as hepatitis B, Epstein-Barr, and cytomegalovirus. This antibody may be used in the study of cell-mediated cytotoxicity and that of immunoregulation and T-lymphocyte-mediated suppression.