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Anti-CD8

SKU: AM261GP Categories: , , ,
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Product Description

The CD8 antigen also known as T8 or Leu2 or Lyt2 or T cell coreceptor is made of ? and ? chain linked by disulphide bond to form ?/? heterdimer of molecular weight 32kD. CD8 is a type 1 member protein in the immunoglobulin supergene family and also plays a role in the process of T-cell mediated killing. CD8 is a stage marker of T cell development in the thymus, and is expressed on ?mature peripheral T cells, most cytotoxic T cells, CD4/CD8+ thymocytes, NK cells and cortical thymocytes. Studies have demonstrated that increased levels of T8+ cells are associated with viral infections such as hepatitis B, Epstein-Barr, and cytomegalovirus. This antibody may be used in the study of cell-mediated cytotoxicity and that of immunoregulation and T-lymphocyte-mediated suppression

Intended Use

IVD

Antibody Type

Monoclonal

Clone

T8

Source

Mouse

Tissue Type/Cancer Type

Frozen Tonsil

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual