The CD8 antigen also known as T8 or Leu2 or Lyt2 or T cell coreceptor is made of ? and ? chain linked by disulphide bond to form ?/? heterdimer of molecular weight 32kD. CD8 is a type 1 member protein in the immunoglobulin supergene family and also plays a role in the process of T-cell mediated killing. CD8 is a stage marker of T cell development in the thymus, and is expressed on ?mature peripheral T cells, most cytotoxic T cells, CD4/CD8+ thymocytes, NK cells and cortical thymocytes. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 ? chain (but not ? chain)
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | SP16 |
| Source | Rabbit |
| Tissue Type/Cancer Type | Tonsil |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
