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Anti-CD79a

SKU: AM414GP Categories: , , ,
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Product Description

CD79a, also known as Ig-alpha, mb-1 membrane glycoprotein, is a type I membrane glycoprotein with a total of 226 amino acids and a molecular weight of 47 kD. CD79a forms a heterodimer with CD79b through disulfide-bonds and further forms a complex in a noncovalent fashion with membrane immunoglobulins. Both CD79a and CD79b are expressed almost exclusively on B cells and B-cell neoplasms. In addition, CD79a and CD79b antibodies are useful markers in the evaluation of precursor B-acute lymphoblastic leukemia (pre-B-ALL) because many of these tumors are negative for other B-cell markers, such as CD20 and CD45RA

Intended Use

IVD

Antibody Type

Monoclonal

Clone

11E 3

Source

Mouse

Tissue Type/Cancer Type

Tonsil

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual