CD79 consist of two proteins, CD79a (mb-1) and CD79b (B29). CD79a recognizes the Ig-alpha protein, and CD79b recognizes the Ig-beta protein of the B-cell antigen component of the B-lymphocyte antigen receptor. The CD79a protein is present on the surface of B-cells throughout their life cycle, and is absent on all other healthy cells, is an excellent marker for identification of normal and neoplastic B lymphocytes. The protein remains present when B-cells transform into active plasma cells, and is also present in virtually all B-cell neoplasms, including B-cell lymphomas, plasmacytomas, and myelomas. It is also present in abnormal lymphocytes associated with some cases of Hodgkin?s disease
Intended Use: IVD
Antibody Type: Monoclonal
Clone: SP18
Source: Rabbit
Tissue Type/Cancer Type: Tonsil