CD79a consists of two proteins, CD79a (mb-1) and CD79b (B29). CD79a recognizes the Ig-alpha protein and CD79b recognizes the Ig-beta protein of the B cell antigen component of the B-lymphocyte antigen receptor. This complex of polypeptides and immunoglobulins constitute the B cell antigen receptor. The two components of this complex are designated CD79a and CD79b. CD79a is an excellent marker for identification of normal and neoplastic B lymphocytes. It has been found to be co-expressed with CD23 in 10% of cases of T-lymphoblastic leukemia/lymphoma. Antibodies to CD79a may also be usedful in the differential diagnosis of Hodgkin?s disease
Intended Use: IVD
Antibody Type: Monoclonal
Clone: EP82
Source: Rabbit
Tissue Type/Cancer Type: Lymph Node