LN2 recognizes the 35 kD Class II invariant chain expressed in the nuclear membrane and cytoplasm of B lymphocytes and is suitable for differentiating between B-cell and T-cell lymphomas. It reacts with a nuclear membrane antigen expressed by B cells of mantle zones and germinal centers, and with the nuclear membrane of interdigitating cells in lymph nodes. It also reacts with Reed-Sternberg cells and their variants in Hodgkin?s disease, and sporadically with antigens expressed by tumor cells of epithelial origin
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | LN2 |
Source | Mouse |
Tissue Type/Cancer Type | Tonsil |
Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |