This antibody reacts with CD71 antigen (also known as T9 or Transferrin Receptor), a homo-dimeric type II membrane protein consisting of two identical sub-units of approximately 95 kD covalently linked by two intermolecular disulfide bonds. Transferrin Receptor is present on 10% of thymocytes, activated lymphocytes, myelocytes, and nucleated erythrocyte precursors. Broad distribution of Transferrin Receptor (TR) has been observed on carcinomas and sarcomas of various origins and malignant lymphomas. Clone H68.4 is specifically directed against the human Transferrin Receptor cytoplasmic tail.
|Tissue Type/Cancer Type|
0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual