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Anti-CD7

SKU: AN761GP Categories: , , ,
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Product Description

Anti-CD7 (SP94) Rabbit Monoclonal Primary Antibody is directed against the 40kD transmembrane glycoprotein, CD7 is majorly expressed on immature and mature T-lymphocytes, and T cell leukemia, natural killer cells, a small subpopulation of normal B cells and on malignant B cells. CD7 gene expresses a transmembrane protein, it is a member of the immunoglobulin superfamily. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3′-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Anti-CD7 (SP94) may be used to aid in the identification of T cell lymphomas

Intended Use

IVD

Antibody Type

Monoclonal

Clone

SP94

Source

Rabbit

Tissue Type/Cancer Type

Tonsil

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual