Monoclonal antibody NK-1 is also called HNK-1 or Leu 7 antigen. It is a 110 kD myeloid, cell-associated surface glycoprotein that recognizes CD57. The antigen is common to leukocytes and neuroectodermal cells. It is present in most cancers with neuronal as well as glial characteristics. Tumors and normal cells derived from the neuroectoderm or the APUD (diffuse neuroendocrine system) tumors also express this antigen. Anti-natural killer cell antibodies used in combination with anti-S-100 antibodies aid in the differentiation of Schwann cell neoplasms from histologically similar fibrosarcomas
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | NK-1 |
Source | Mouse |
Tissue Type/Cancer Type | Tonsil |
Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |