This antibody recognizes a 185 kD molecule (CD45RO) which occurs on mature activated T cells, most thymocytes, and a sub-population of resting T cells within both the CD-4 and CD-8 subsets. UCHL-1 shows no reactivity with normal B or NK cells, but will react with granulocytes and monocytes. This antibody can be used as a marker of T cell lymphomas and other T cell neoplasms. The antigen has been shown to be immunologically unrelated to the lymphocyte-function-associated antigen (LFA-1), which has a similar molecular weight.
|Tissue Type/Cancer Type|
0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual