CD41 or Integrin alpha chain 2b is a hetero dimeric integral membrane protein. In presence of Ca2+ ion, this protein forms a heterodimer complex (GPIIIb-IIIa) with GPIIIa. This complex will interact to one of the four different adhesive proteins (i.e., fibronectin, von Willebrand factor [Vwf], fibrinogen, or vitronectin. CD41 is majorly expressed on cell membranes of megakaryocytes, platelets, and embryonic hematopoietic stem cells. The integrin alpha chain plays a crucial role in coagulation through its intermediary molecules
Intended Use | IVD |
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Antibody Type | Monoclonal |
Clone | EP178 |
Source | Rabbit |
Tissue Type/Cancer Type | Spleen Ca |
Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |