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Anti-CD4

SKU: AN722GP Categories: , , ,
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Product Description

CD4 (cluster of differentiation 4) is a glycoprotein present on the surface of immune cells like ?macrophages, T helper cells, monocytes, and dendritic cells. In lymphatic tissue systems, the CD4 positive T cells are found in big numbers in the parafollicular zone, while in the germinal centers and mantle zone CD4 positive T cells are found scattered. CD4 ?marker is expressed on a T-cell subset (helper/inducer) and is found in approximately 80% of thymocytes and in 45% of peripheral blood lymphocytes. CD4 is expressed in the majoritiy of T-cell lymphomas, including mycosis fungoides, lymphomas are CD4 positive with the exception of aggressive NK-cell leukemia and extranoda NK/T-cell lympohoma. CD4 plays an important role in the classification of lymphocytes in inflammatory lesions and malignant lymphomas

Intended Use

IVD

Antibody Type

Monoclonal

Clone

EP204

Source

Rabbit

Tissue Type/Cancer Type

Tonsil

Pack

0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual