CD31 is platelet and endothelial cell adhesion molecule 1 (also known as PECAM-1), part of the immunoglobulin super family, which is involved in leukocyte migration, angiogenesis and integrin activation. It is found on the surface of platelets, monocytes, neutrophils and some type of T-cells. CD31 has various roles in vascular biology including angiogenesis, platelet function, and thrombosis. Due to the positive correlation between CD31 expression on monocytes and angiogenesis of tumors, immunohistochemical staining of CD31 can prove as a useful tool to predict the possibility of metastatic tumor angiogenesis.
Intended Use: IVD
Antibody Type: Monoclonal
Clone: C31.3+C31.7+C31.10
Source: Mouse
Tissue Type/Cancer Type: Tonsil