DatasheetSDS

CD31, also known as PECAM-1 (platelet endothelial cell adhesion molecule 1) is a transmembrane glycoprotein belongs to immunoglobulin supergene family of adhesion molecules. The stem cells in hematopoietic system express CD31 which are used for identifying and determining concentration of these cells for bone marrow transplantation and experimental studies. The expression of CD31 is found on normal, benign and malignant endothelial cells and hence, considered to be a sensitive and specific marker for vascular differentiation. The CD31 expression levels determine the extent of tumor angiogenesis and imply rapidly growing tumor and a predictor of tumor recurrence.