Anti- CD269
CD269, also known as BCMA (B cell maturation antigen) or TNFRSF17 (Tumor necrosis factor receptor superfamily member 17) is a 27 kD type I integral transmembrane glycoprotein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. Upon binding to its ligands, CD269 activates NF-kB and c-Jun N-terminal kinase and thus leads to B cell development and survival. It is expressed in mature B-lymphocytes, plasmablasts and plasma cells.
Intended Use | IVD |
---|---|
Antibody Type | Monoclonal |
Clone | BCMA/2366 |
Source | Mouse |
Tissue Type/Cancer Type | Colon Tissue |
Pack | 6 mL – Manual – RTU, 100 Tests – Automation – i6000, 1 mL – Manual – Concentrate, 0.5 mL – Manual – Concentrate, 50 Tests – Automation – Xmatrx, 50 tests – NanoVIP®, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |