CD23 is a type II membrane glycoprotein which functions as a receptor for IgE and for lymphocyte growth factor. CD23 plays important role in B cell activation and growth. CD23 can be positive on B lymphocyte, monocytes, macrophages, follicular dendritic cells, T cell subsets. CD23 staining is applied in the differentiation of small lymphocytic lymphomas (SLL) and mantle cell lymphoma. CD23 expression can be detected in SLL, mediastinal large B cell lymphoma, and lymphoplasmacytic lymphoma.
|Tissue Type/Cancer Type|
0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 200 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual