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The CD22 antigen also known as BL-CAM is a single chain type I transmembrane molecule which contains seven Ig-like domains and molecular weight of 130 to 140kD. In humans, IgM(+) IgD(+) B cells express cell-surface CD22. CD22 molecule is suggested as a component of the B-cell activation complex and as an adhesion molecule. In B-cell malignancies, CD22 marker varies from 60% to 80% depending on the histological type and on the assays used. CD22 antigen is weakly expressed in myeloid leukemias and non-T cell acute lymphoblastic leukemias and is strongly expressed in hairy cell leukaemias. It is absent on peripheral blood T cells, T cell leukemias, granulocytes and monocytes
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | FPC1 |
| Source | Mouse |
| Tissue Type/Cancer Type | Tonsil |
| Pack | 0.5 mL – Manual – Concentrate, 1 mL – Manual – Concentrate, 6 mL – Manual – RTU, 50 Tests – Automation – Xmatrx, 100 Tests – Automation – i6000, 160 Tests – Automation – Xmatrx, 5 slides – Xmatrx, 5 slides – Manual |
