CD21 is a single-pass type 2 transmembrane protein that serves as the complement receptor for C3d and the Epstein-Barr virus. Anti-CD21 is valuable in differentiating follicular lymphoma with marginal zone differentiation from marginal zone lymphoma with follicular involvement. It also plays a role in separating among nodular lymphocyte predominant Hodgkin lymphoma, lymphocyte-rich classic Hodgkin lymphoma, and T-cell/histiocyte-rich B-cell lymphoma in combination with other B-cell and T-cell markers. The antigen is absent on T-Lymphocytes, monocytes, and granulocytes.
| Intended Use | IVD |
|---|---|
| Antibody Type | Monoclonal |
| Clone | RM372 |
| Source | Rabbit |
| Tissue Type/Cancer Type | TONSIL |
| Pack | 6 mL (RTU), 100 Tests – Automation – i6000, 1 mL(Conc.), 0.5 mL (Conc.), 160 tests – Xmatrx Elite, 50 tests – Xmatrx Elite, 5 slides ? Xmatrx, 5 slides ? Manual |
